Author Archives: Valentina Alex

New tool more accurately uses genomic data to predict disease risk across diverse populations: Integrating data from different ancestries reduces bias in predicting disease risk

Polygenic risk scores (PRS) are promising tools for predicting disease risk, but current versions have built-in bias that can affect their accuracy in some populations and result in health disparities. However, a team of researchers from Massachusetts General Hospital (MGH), the Broad Institute of MIT and Harvard, and Shanghai Jiao Tong University in Shanghai, China,… Read More »

Breaking the shield that protects pancreatic cancer from immunotherapy

Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study led by UT Southwestern researchers suggests. The findings, published in Cancer Cell, could offer a new strategy to fight pancreatic cancer, a deadly… Read More »

Patient-derived micro-organospheres enable cutting-edge precision oncology

A patient’s tumor cell response to therapy is affected by many factors, including genetic alterations, tumor microenvironment, and intratumoral heterogeneity. This can make it extremely difficult to determine optimum treatment regimens, amidst the ever-increasing number of drug candidates and cancer therapies that have recently been developed. Added to these challenges is the limited timeframe in… Read More »

Social media break improves mental health, study suggests

Asking people to stop using social media for just one week could lead to significant improvements in their wellbeing, depression and anxiety and could, in the future, be recommended as a way to help people manage their mental health say the authors of a new study. The study, carried out by a team of researchers… Read More »